If we were to talk about how much of a hazard ratio do these bring to you in terms of all-cause mortality ... Hypertension is about 20%. Type 2 diabetes is about a 30% increase in mortality. Smoking is a 50% increase. Being weak relative to being strong is about 250%. Having a very low VO2 max—in the bottom 25% of the population versus being in the top 2.5%— of the population is about 400%.