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THC and CBD, when they're brought into the brain and body... they bind to those receptors, those endogenous cannabinoid receptors, and they tap into the same systems that your endogenous cannabinoids would tap into—the ones that affect mood and energy and creativity and relaxation, etc.—but they do so with thousand-fold greater
potency...
Andrew Huberman
THC & CBD Out-Compete the Body's Endogenous Cannabinoid System for Receptor Binding
The Effects of Cannabis (Marijuana) on the Brain & Body
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